Cryptic crossword clue
Use less MDMA? Come on, silly, one’s consumed by it! 9

The most common and most likely answer to this crossword clue is the 9 letter word ECONOMISE

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Use less" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case use less = economise.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ECONOMISE mean?

ECONOMISE verb
  1. To practice being economical (by using things sparingly or in moderation, and by avoiding waste or extravagance).
  2. To use frugally.

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