The most common and most likely answer to this crossword clue is the 6 plus 8 letter word BEYOND CONTEMPT
I've seen this crossword clue in The Daily Telegraph
B
E
Y
O
N
D
C
O
N
T
E
M
P
T
Buddy explains!
The straight part
We know that "Utterly despicable" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case utterly despicable = beyond contempt.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.