Cryptic crossword clue
V-sign shows one is not in agreement! 6

The most common and most likely answer to this crossword clue is the 6 letter word VARIES

I've seen this crossword clue in The Daily Telegraph
V
A
R
I
E
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VARIES mean?

VARIES verb
  1. To change with time or a similar parameter.
  2. To institute a change in, from a current state; to modify.
  3. Not to remain constant: to change with time or a similar parameter.
  4. (of the members of a group) To display differences.
  5. To be or act different from the usual.
  6. To make of different kinds; to make different from one another; to diversity; to variegate.
  7. To embellish; to change fancifully; to present under new aspects, as of form, key, measure, etc. See variation.
  8. To disagree; to be at variance or in dissension.

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