Cryptic crossword clue
Vacuous extract from Carolina newspaper

The most common and most likely answer to this crossword clue is the 5 letter word INANE

I've seen this crossword clue in The Guardian
I
N
A
N
E


Buddy explains!

The straight part
We know that "Vacuous" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case vacuous = inane.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INANE mean?

INANE noun
  1. That which is void or empty.
INANE adjective
  1. Lacking sense or meaning (often to the point of boredom or annoyance)
  2. Purposeless; pointless

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