The most common and most likely answer to this crossword clue is the 4 letter word OBOE
I've seen this crossword clue in Financial Times
O
B
O
E
More clues leading to the result OBOE
- Order parts for old instrument
- Orchestra's leader invested in gong? Blow me!
- Comb, note, regularly chosen for musical instrument
- Something instrumental in rejection of neo-bourgeoisie
- Cockney's bum note, one in orchestra
- Leader of orchestra regularly broke wind
- Instrument’s top broke, not every other part
- Gong drowning old wind instrument
- Instrument that's round? Gong's round
- Musical instrument, gong, keeping its shape
Buddy explains!

The straight part
We know that "instrument" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case instrument = oboe.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does OBOE mean?
OBOE noun- A soprano and melody wind instrument in the modern orchestra and wind ensemble. It is a smaller instrument and generally made of grenadilla wood. It is a member of the double reed family.