The most common and most likely answer to this crossword clue is the 4 letter word ESAU
E
S
A
U
More clues leading to the result ESAU
- Biblical character appearing in thesaurus
- Service revolving around a biblical man
- Hairy man in the sauna
- Hairy brother in Continental group without specific appeal?
- Twin succeeded in Uganda
- Rebecca’s son seen in smoke sauna
- Isaacson’s appeal accepted in Brussels?
- Might he be found under 'hairy' in thesaurus?
- Biblical brother cheated in games, audaciously
- Isaac’s son’s particular appeal in Europe
Buddy explains!

The straight part
We know that "wronged brother" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case wronged brother = esau.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.