Cryptic crossword clue
Varied rates putting off a dodgy purchaser of space in newspaper 10

The most common and most likely answer to this crossword clue is the 10 letter word ADVERTISER

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "purchaser of space in newspaper" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case purchaser of space in newspaper = advertiser.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ADVERTISER mean?

ADVERTISER noun
  1. One who advertises.
  2. A periodical in which advertisements can be published by individuals.

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