Cryptic crossword clue
Varieties left to go to ruin? On the contrary 10

The most common and most likely answer to this crossword clue is the 10 letter word REVITALISE

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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Crossword Answer definitions

REVITALISE verb
  1. To give new life, energy, activity or success to something.
  2. To rouse from a state of inactivity or quiescence.

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