The most common and most likely answer to this crossword clue is the 5 letter word EVITA
E
V
I
T
A
More clues leading to the result EVITA
- Musical entertainment viewed in the Adelphi originally?
- Show half of cumulative returns
- Show thanks after I have turned up
- Girl taking in Italian show
- She would display initiative finally in revolution
- Echo life of e.g. Verdi in musical
- South American figure turned up at four after end of debate
- Musical relatively free of trappings on reflection
- Musical beat I verbalise partly, making comeback
- She showed some initiative in revolution
Buddy explains!

The straight part
We know that "Vehicle for Madonna" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case vehicle for madonna = evita.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.