Cryptic crossword clue
Venture into Microsoft's domain is trouble for corporation 9

The most common and most likely answer to this crossword clue is the 9 letter word ENTERITIS

I've seen this crossword clue in The Times
E
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Buddy explains!

The straight part
We know that "trouble for corporation" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case trouble for corporation = enteritis.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ENTERITIS mean?

ENTERITIS noun
  1. Inflammation of the intestines, generally the small intestine, that may lead to diarrhea.

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