The most common and most likely answer to this crossword clue is the 6 letter word VENICE
I've seen this crossword clue in The Guardian
V
E
N
I
C
E
More clues leading to the result VENICE
- European residing in very pleasant Italian city
- City is very English, previously hazardous
- Railway out of extremely pleasant place with canals
- Extremely visitable, pleasant Italian city
- Very English resort, a major tourist attraction
- Lose track of exceptionally fine port
- Very early start by Mediterranean city, a major tourist destination
- Very European city on the coast is novel’s deadly location
- City, European, very pleasant to go around?
- Very agreeable to take in European tourist destination
Buddy explains!
The straight part
We know that "a major tourist destination" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a major tourist destination = venice.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.