Cryptic crossword clue
Very important things, aiding life support initially 6

The most common and most likely answer to this crossword clue is the 6 letter word VITALS

I've seen this crossword clue in The Daily Telegraph
V
I
T
A
L
S


Buddy explains!

The straight part
We know that "Very important things" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case very important things = vitals.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VITALS mean?

VITALS noun
  1. Those organs of the body that are essential for life.
  2. Those parts of a system without which it cannot function.
  3. Vital signs.

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