Cryptic crossword clue
Very much against the pointless subject of “rickrolling” 6

The most common and most likely answer to this crossword clue is the 6 letter word VASTLY

I've seen this crossword clue in The Guardian
V
A
S
T
L
Y

Buddy explains!

The straight part
We know that "Very much/Very much" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case very much/very much = vastly.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VASTLY mean?

VASTLY adverb
  1. Greatly, in a vast manner.

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