Cryptic crossword clue
Very old houses set to be de­molished — that’s a blow 8

The most common and most likely answer to this crossword clue is the 8 letter word EASTERLY

I've seen this crossword clue in The Guardian
E
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Buddy explains!

The straight part
We know that "a blow" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a blow = easterly.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EASTERLY mean?

EASTERLY noun
  1. Any persistent wind from the east (usually applied to broad currents or belts of easterly winds).
EASTERLY adjective
  1. Facing the east; directed towards the east.
  2. Located towards the east.
  3. Coming from the east.
EASTERLY adverb
  1. In an eastward direction or position; towards the east.
  2. From the east.

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