Cryptic crossword clue
Vespucci bore a nautical upbringing, somewhat lacking in inspiration? 9

The most common and most likely answer to this crossword clue is the 9 letter word ANAEROBIC

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Buddy explains!

The straight part
We know that "lacking in inspiration" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lacking in inspiration = anaerobic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ANAEROBIC mean?

ANAEROBIC adjective
  1. Without oxygen; especially of an environment or organism.
  2. Of exercise, involving glycolysis (the conversion of glucose to adenosine triphosphate) rather than using oxygen to supply bodily energy needs.
  3. Of or relating to an anaerobe.

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