Cryptic crossword clue
Vest husband wears at home before retiring 6

The most common and most likely answer to this crossword clue is the 6 letter word INHERE

I
N
H
E
R
E

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The straight part
We know that "Vest" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case vest = inhere.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INHERE mean?

INHERE verb
  1. To be inherent; to be an essential or intrinsic part of; to be fixed or permanently incorporated with something

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