The most common and most likely answer to this crossword clue is the 7 letter word VINEGAR
V
I
N
E
G
A
R
More clues leading to the result VINEGAR
- Source of grapes, fish and sour-tasting liquid
- Half a dozen close by imbibing good or bad wine?
- Condiment given a shaking, right?
- Vigorin volume in vogue upset
- Storm about backing foreign plonk, sour stuff
- Versace’s first in fashion, revolutionary dressing
- Very popular revolutionary fashion? It’s sharp stuff
- Very fine female lost rag over sauce
- Sour stuff very shortly happening, with anger rising
- Mistakenly given another case of wine that’s gone off
Buddy explains!

The straight part
We know that "Vigor" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case vigor = vinegar.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does VINEGAR mean?
VINEGAR noun- A sour liquid formed by the fermentation of alcohol used as a condiment or preservative; a dilute solution of acetic acid.
- Any variety of vinegar.
- To season or otherwise treat with vinegar.