The most common and most likely answer to this crossword clue is the 7 letter word HEINOUS
I've seen this crossword clue in The Times
H
E
I
N
O
U
S
More clues leading to the result HEINOUS
- Wicked male and one with common sense
- Contemptible chap in love with States
- Terrible in-house squabbling
- Appalling hotel that is recalled by us abroad
- Ambassador across Atlantic admits nothing shocking
- Ambassador beginning to ignore common sense? Disgraceful
- A man with common sense holds one to be shocking
- Vile dwelling shortly to have a German as tenant
- Man I mind, as hateful
- Wicked man’s in love with American
Buddy explains!

The straight part
We know that "Vile" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case vile = heinous.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HEINOUS mean?
HEINOUS adjective- Totally reprehensible.