Cryptic crossword clue
Vineyard Frenchwoman runs with less compassion 8

The most common and most likely answer to this crossword clue is the 8 letter word CRUELLER

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "with less compassion" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with less compassion = crueller.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CRUELLER mean?

CRUELLER adjective
  1. Intentionally causing or reveling in pain and suffering; merciless, heartless.
  2. Harsh; severe.
  3. Cool; awesome; neat.

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