The most common and most likely answer to this crossword clue is the 4 letter word NUKE
I've seen this crossword clue in The Times
N
U
K
E
More clues leading to the result NUKE
- Violently destroy new instrument
- Bomb from this country in North East
- Instrument placed on nitrogen bomb
- Viciously attack note on instrument
- . Weapon United Kingdom hid in the north east
- North eastern UK is devastated by modern day weapon
- Bomb is undug, keep checking at regular intervals
- Going westward in trek under attack
- An atomic bomb is no instrument to use on an island
- Slash the odds of unluckier attack
Buddy explains!

The straight part
We know that "Violently destroy" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case violently destroy = nuke.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does NUKE mean?
NUKE noun- A nuclear weapon.
- (by extension) Something that destroys or negates, especially on a catastrophic scale.
- A nuclear power station.
- A vessel such as a ship or submarine running on nuclear power.
- A person (such as a sailor in a navy or a scientist) who works with nuclear weapons or nuclear power.
- A microwave oven.
- To use a nuclear weapon on a target.
- To destroy or erase completely.
- (by extension) To carry out a denial-of-service attack against (an IRC user).
- To expose to some form of radiation.
- To cook in a microwave oven.
- To over-analyze or overly despair over something.
- A nucleus colony; a small bee colony created from a larger colony.
- The spinal cord.
- The back of the neck, the nape; of an animal: the back of the head or the portion of the body behind the head.
- A small corner formed by two walls; an alcove.
- A hidden or secluded spot; a secluded retreat.
- A recess, cove or hollow.
- An English unit of land area, originally 1/4 of a yardland but later 12 1/2 or 20 acres.
- A corner of a piece of land; an angled piece of land, especially one extending into other land.