Cryptic crossword clue
Virus “V,” or devious one who makes it? 8

The most common and most likely answer to this crossword clue is the 8 letter word SURVIVOR

S
U
R
V
I
V
O
R

Buddy explains!

The straight part
We know that "one who makes it" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one who makes it = survivor.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SURVIVOR mean?

SURVIVOR noun
  1. One who survives, especially one who survives a traumatic experience.
  2. A person who is able to endure hardship.
  3. One who knew a specific decedent.

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