The most common and most likely answer to this crossword clue is the 5 letter word VERVE
I've seen this crossword clue in The Guardian
V
E
R
V
E
More clues leading to the result VERVE
- Animation shown where monkey loses tail
- Energy equals discharged voltage doubled, divided by resistance
- Energy of cover version
- Vitality of revolutionary always having internal resistance
- Cover version’s vitality
- Dash or run to be involved in the day victory came twice
- Enthusiasm over velvet coats
- May 8th “Celebration Sandwiches” recipe produces excitement
Buddy explains!

The straight part
We know that "Vitality" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case vitality = verve.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does VERVE mean?
VERVE noun- Excitement of imagination such as that which animates a poet, artist, or musician, in composing or performing
- Artistic energy and enthusiasm
- Vigour, vitality and liveliness
- Rapture, enthusiasm
- Spirit, energy