The most common and most likely answer to this crossword clue is the 6 letter word NIACIN
I've seen this crossword clue in Independent
N
I
A
C
I
N
More clues leading to the result NIACIN
- Acid in can I spilt
- Vitamin in one way and another gives protection for a cold
- Almost a crime, we’re told, to provide vitamin
- Vitamin B, A and C twice in mixture
- Vitamin taken orally, it’s nearly agreed?
- Chain redeveloped hotel abandoned in part of complex
- Biblical killer turns up in supplement
- Vitamin C in regular treatment for angina, initially
- Vitamin A and C dropped into eyes, they said in news
- Vitamin from arnica intensely revolting
Buddy explains!

The straight part
We know that "Vitamin" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case vitamin = niacin.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does NIACIN mean?
NIACIN noun- A water-soluble vitamin, a component of vitamin B complex, found in meat, yeast, and dairy products; it is essential to metabolism.