Cryptic crossword clue
Vitamin in one way and another gives protection for a cold 6

The most common and most likely answer to this crossword clue is the 6 letter word NIACIN

I've seen this crossword clue in Independent
N
I
A
C
I
N


Buddy explains!

The straight part
We know that "Vitamin" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case vitamin = niacin.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NIACIN mean?

NIACIN noun
  1. A water-soluble vitamin, a component of vitamin B complex, found in meat, yeast, and dairy products; it is essential to metabolism.

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