The most common and most likely answer to this crossword clue is the 7 letter word ACETONE
I've seen this crossword clue in The Times
A
C
E
T
O
N
E
More clues leading to the result ACETONE
- Excellent quality organic compound
- Volatile stuff Blair commonly has expert overlook
- Wicked, close to bankrupt individual is solvent
- Solvent one takes to Tyneside
- Expert needing to make firm solvent
- Something that dissolves, once mixed with tea
- Thinner expert has style
- Solvent of superb quality
- One colouring is an organic solvent
- Organic compound, fine quality
Buddy explains!

The straight part
We know that "Volatile stuff" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case volatile stuff = acetone.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ACETONE mean?
ACETONE noun- A colourless, volatile, flammable liquid ketone, (CH3)2CO, used as a solvent.