The most common and most likely answer to this crossword clue is the 2 letter word RE
R
E
More clues leading to the result RE
- Tender women carelessly giving another gift
- Tenant going round back of house to get in again
- Get back in swing, ticker turning over regularly
- Energy-filled landlord's due to hold forth — he's tried before
- Tenant wanting extra energy to appear again
- Appear again, as army corps heading north to meet another southbound
- Reverberation from breech? OK
- Some screen terminals provide a second input
- Staggered about European Court sitting again
- Run across again, never returning in opposite direction
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does RE mean?
RE preposition- About, regarding, with reference to; especially in letters, documents and emails.
- A syllable used in solfège to represent the second note of a major scale.
- Reinsurance.