The most common and most likely answer to this crossword clue is the 6 letter word HASSLE
H
A
S
S
L
E
More clues leading to the result HASSLE
- Fool in hospital left ecstasy — bother
- Ship entering sound exhibiting difficulty
- Well, going round ship is a problem
- Lashes out when there is trouble
- Feel shares must go up without any problem
- Harry lashes out
- Owns toboggan, endless bother
- Badger lashes out
- Harry possesses silver, oddly
- Harry interrupts Martha’s sleep
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HASSLE mean?
HASSLE noun- Trouble, bother, unwanted annoyances or problems.
- A fight or argument.
- An action which is not worth the difficulty involved.
- To trouble, to bother, to annoy.
- To pick a fight or start an argument.