The most common and most likely answer to this crossword clue is the 9 letter word DESPAIRED
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More clues leading to the result DESPAIRED
- Wanted around Panama, lost hope
- Lost hope after pater consumed by wish to join daughter
- Gave up having incorrectly read previous solution
- Southern couple, during performance, lost heart
- Gave up hope, seeing legal document cut by second couple
- Gave up hope, seeing second couple in action
- One embarrassed after spade’s dealt out – didn’t have heart
- Lost all hope of French head of state having made an agreement to abstain
- Southern duo, caught in act, gave up hope
- In the beginning, serpent and pair caught in act and lost hope
Buddy explains!

The straight part
We know that "lost hope" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lost hope = despaired.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DESPAIRED mean?
DESPAIRED verb- To give up as beyond hope or expectation; to despair of.
- To cause to despair.
- (often with “of”) To be hopeless; to have no hope; to give up all hope or expectation.