The most common and most likely answer to this crossword clue is the 12 letter word CARAVANSERAI
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More clues leading to the result CARAVANSERAI
Buddy explains!

The straight part
We know that "Wayside inn" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case wayside inn = caravanserai.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CARAVANSERAI mean?
CARAVANSERAI noun- A roadside inn having a central courtyard where caravans can rest.
- An upscale hotel.
- A home or shelter for caravans.