The most common and most likely answer to this crossword clue is the 4 letter word WIFE
I've seen this crossword clue in The Daily Telegraph
W
I
F
E
More clues leading to the result WIFE
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does WIFE mean?
WIFE noun- A married woman, especially in relation to her spouse.
- The female of a pair of mated animals.
- (said of men) to marry
- An adult female human.
- (collective) All females collectively; womankind.
- A female person, usually an adult; a (generally adult) female sentient being, whether human, supernatural, elf, alien, etc.
- A wife (or sometimes a fiancée or girlfriend).
- A female who is extremely fond of or devoted to a specified type of thing. (Used as the last element of a compound.)
- A female attendant or servant.