The most common and most likely answer to this crossword clue is the 5 letter word OPRAH
I've seen this crossword clue in The Guardian
O
P
R
A
H
More clues leading to the result OPRAH
- TV personality’s revolutionary version of Marx
- Wealthy American‘s brother keeping silent in turn
- Influential American wants one of Groucho’s kin sent into retirement
- Silent film star falls head over heels for chat show host
- Silent entertainer comes around and turns into talkative one
- One of the Marx brothers making a comeback as talk show host
- Daytime TV show one of the Marx brothers brought back
- Media mogul's operation leads to cheer
Buddy explains!

The straight part
We know that "Wealthy American" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case wealthy american = oprah.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.