Cryptic crossword clue
Wearing underwear, I got in a tangle looking for evidence 13

The most common and most likely answer to this crossword clue is the 13 letter word INVESTIGATION

I've seen this crossword clue in Independent
I
N
V
E
S
T
I
G
A
T
I
O
N

Buddy explains!

The straight part
We know that "looking for evidence" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case looking for evidence = investigation.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INVESTIGATION mean?

INVESTIGATION noun
  1. The act of investigating; the process of inquiring into or following up; research, especially patient or thorough inquiry or examination

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