Cryptic crossword clue
Weary expression on trip taking in English house 5-2

The most common and most likely answer to this crossword clue is the 5 letter word HEIGH

I've seen this crossword clue in The Daily Telegraph
H
E
I
G
H

Buddy explains!

The straight part
We know that "Weary expression" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case weary expression = heigh.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HEIGH mean?

HEIGH interjection
  1. An exclamation designed to call attention, give encouragement, etc.

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