The most common and most likely answer to this crossword clue is the 6 letter word STALED
S
T
A
L
E
D
Buddy explains!
The straight part
We know that "Weed" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case weed = staled.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does STALED mean?
STALED verb- (of alcohol) To make stale; to age in order to clear and strengthen (a drink, especially beer).
- To make stale; to cause to go out of fashion or currency; to diminish the novelty or interest of, particularly by excessive exposure or consumption.
- To become stale; to grow odious from excessive exposure or consumption.
- (alcohol) To become stale; to grow unpleasant from age.
- To make a ladder by joining rungs ("stales") between the posts.
- To stalemate.
- To be stalemated.
- (livestock) To urinate, especially used of horses and cattle.
- To serve as a decoy, to lure.