Cryptic crossword clue
We'll take a break about one, being most exhausted 8

The most common and most likely answer to this crossword clue is the 8 letter word WEARIEST

I've seen this crossword clue in The Times
W
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Buddy explains!

The straight part
We know that "most exhausted" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case most exhausted = weariest.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WEARIEST mean?

WEARIEST adjective
  1. Having the strength exhausted by toil or exertion; tired; fatigued.
  2. Having one's patience, relish, or contentment exhausted; tired; sick.
  3. Expressive of fatigue.
  4. Causing weariness; tiresome.

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