The most common and most likely answer to this crossword clue is the 7 letter word AMOEBAE
I've seen this crossword clue in The Daily Telegraph
A
M
O
E
B
A
E
More clues leading to the result AMOEBAE
Buddy explains!

The straight part
We know that "unsophisticated beings" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case unsophisticated beings = amoebae.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does AMOEBAE mean?
AMOEBAE noun- A member of the genus Amoeba of unicellular protozoa that moves by means of temporary projections called pseudopodia.
- The graph of the real part of the logarithms of a polynomial equation in complex numbers.
- An asexual.