Cryptic crossword clue
What Jolson’s mother did in a northern region 6

The most common and most likely answer to this crossword clue is the 6 letter word BOREAL

B
O
R
E
A
L

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The straight part
We know that "northern region" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case northern region = boreal.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BOREAL mean?

BOREAL adjective
  1. Of, relating to, or coming from the north.

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