Cryptic crossword clue
What one with the biggest mouth does is extreme

The most common and most likely answer to this crossword clue is the 9 letter word UTTERMOST

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "What one with the biggest mouth does/extreme" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case what one with the biggest mouth does/extreme = uttermost.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UTTERMOST mean?

UTTERMOST noun
  1. The utmost; the highest or greatest degree; the farthest extent.
UTTERMOST adjective
  1. Outermost.
  2. Extreme; utmost; of the farthest, greatest, or highest degree.

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