The most common and most likely answer to this crossword clue is the 10 letter word EXPERIENCE
I've seen this crossword clue in The Daily Telegraph
E
X
P
E
R
I
E
N
C
E
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does EXPERIENCE mean?
EXPERIENCE noun- The effect upon the judgment or feelings produced by any event, whether witnessed or participated in; personal and direct impressions as contrasted with description or fancies; personal acquaintance; actual enjoyment or suffering.
- An activity one has performed.
- A collection of events and/or activities from which an individual or group may gather knowledge, opinions, and skills.
- The knowledge thus gathered.
- Trial; a test or experiment.
- To observe certain events; undergo a certain feeling or process; or perform certain actions that may alter one or contribute to one's knowledge, opinions, or skills.