Cryptic crossword clue
What’s anathema to vegans, useless as opening 6

The most common and most likely answer to this crossword clue is the 6 letter word MEATUS

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Buddy explains!

The straight part
We know that "opening" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case opening = meatus.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MEATUS mean?

MEATUS noun
  1. A tubular opening or passage in the body.

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