Cryptic crossword clue
What’s gone is one 26 6

The most common and most likely answer to this crossword clue is the 6 letter word PASTIS

P
A
S
T
I
S


Buddy explains!

The straight part
We know that "one 26" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one 26 = pastis.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PASTIS mean?

PASTIS noun
  1. A liqueur containing aniseed.

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