Cryptic crossword clue
What’s turned up in morning-after pill box? 4

The most common and most likely answer to this crossword clue is the 4 letter word INRO

I
N
R
O

Buddy explains!

The straight part
We know that "pill box" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case pill box = inro.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INRO mean?

INRO noun
  1. A small decorative box, hung from the sash of a kimono, for holding small objects

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