The most common and most likely answer to this crossword clue is the 5 plus 7 letter word THREE WITCHES
I've seen this crossword clue in Financial Times
T
H
R
E
E
W
I
T
C
H
E
S
Buddy explains!
The straight part
We know that "weird sisters" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case weird sisters = three witches.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.