The most common and most likely answer to this crossword clue is the 3 letter word ASP
A
S
P
More clues leading to the result ASP
- Something put in Christmas pudding is poisonous
- Has pity, locking away poisoner
- Like quiet poisoner
- File does not include river snake.
- Poisoner in Cleopatra's presence
- When pressure generated by snake
- Predatory fish, key species
- Venomous creature like viper, at heart
- Heads off awful snake, poisonous - this one?
- Like piano used for Killer Queen? Quite the opposite, allegedly
Buddy explains!

The straight part
We know that "snake" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case snake = asp.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ASP mean?
ASP noun- A water snake.
- A venomous viper native to southwestern Europe (Vipera aspis).
- The Egyptian cobra (Naja haje)
- A type of European fish (Aspius aspius).
- The aspen tree.