The most common and most likely answer to this crossword clue is the 6 letter word ANNUAL
A
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More clues leading to the result ANNUAL
- Publication with record of events involving university
- A nun ordered a large yearbook
- Yearly, see a nun swimming in a lake
- Cancel binding a yearbook
- Declare invalid must have blood type checked yearly
- Declare invalid having to check blood type yearly
- When startled, pets rejected unpleasant modified lettuce, perhaps
- Garden-flower periodical
- Cancel without a regular publication
- Awning usable at regular intervals yearly
Buddy explains!

The straight part
We know that "lettuce, perhaps" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lettuce, perhaps = annual.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ANNUAL mean?
ANNUAL noun- An annual publication; a book, periodical, journal, report, comic book, yearbook, etc., which is published serially once a year, which may or may not be in addition to regular weekly or monthly publication.
- An annual plant; a plant with a life span of just one growing season; a plant which naturally germinates, flowers and dies in one year. Compare biennial, perennial.
- A medical checkup taking place once a year.
- A pantomime taking place once a year.
- Happening once every year.
- Of, for, or relating to a whole year, often as a recurring cycle; determined or reckoned by the year; accumulating in the course of a year; performed, executed, or completed over the course of a year. See also circannual.
- (of a plant) Having a life cycle that is completed in only one growing season; e.g. beans, corn, marigold. See Annual plant in Wikipedia. Compare biennial, perennial.
- Living or lasting just one season or year, as certain insects or insect colonies.