Cryptic crossword clue
When Toughies come out, needing 25% extra time, feeble bewilderment may be heard 8

The most common and most likely answer to this crossword clue is the 8 letter word WEEKDAYS

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Buddy explains!

The straight part
We know that "When Toughies come out, needing 25% extra time" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case when toughies come out, needing 25% extra time = weekdays.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WEEKDAYS mean?

WEEKDAYS noun
  1. A day of the week except those which form the weekend; that is:
  2. Any day of the week (Monday through Sunday).
WEEKDAYS adverb
  1. On weekdays.

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