Cryptic crossword clue
When you’re out of this, you’re not with it, on balance 6

The most common and most likely answer to this crossword clue is the 6 letter word KILTER

I've seen this crossword clue in The Daily Telegraph
K
I
L
T
E
R


Buddy explains!

The straight part
We know that "When you’re out of this, you’re not with it, on balance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case when you’re out of this, you’re not with it, on balance = kilter.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does KILTER mean?

KILTER noun
  1. (usually in the negative) (Good) condition, form, or order; fettle.
  2. A hand of playing cards which is useless; a dead man's hand.

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