Cryptic crossword clue
Whimsically Cain became one east of Eden escorting stranger 6

The most common and most likely answer to this crossword clue is the 6 letter word NODDER

N
O
D
D
E
R

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The straight part
We know that "Whimsically Cain became one" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case whimsically cain became one = nodder.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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