Cryptic crossword clue
Whistleblower runs, busy and able to change direction 10

The most common and most likely answer to this crossword clue is the 10 letter word REFRACTIVE

I've seen this crossword clue in The Guardian
R
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A
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Buddy explains!

The straight part
We know that "able to change direction" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case able to change direction = refractive.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REFRACTIVE mean?

REFRACTIVE adjective
  1. That refracts; causing or relating to refraction.

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