Cryptic crossword clue
Who can fill an empty beer jug? 6

The most common and most likely answer to this crossword clue is the 6 letter word BREWER

I've seen this crossword clue in The Guardian
B
R
E
W
E
R


Buddy explains!

The straight part
We know that "Who can fill an empty beer jug" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case who can fill an empty beer jug = brewer.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BREWER mean?

BREWER noun
  1. Someone who brews, or whose occupation is to prepare malt liquors.

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