Cryptic crossword clue
Wine I substituted for lost love, doctor! 5

The most common and most likely answer to this crossword clue is the 5 letter word MEDIC

I've seen this crossword clue in Financial Times
M
E
D
I
C


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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MEDIC mean?

MEDIC noun
  1. A doctor.
  2. A paramedic, someone with special training in first aid, especially in the military.
  3. A medical student.
MEDIC adjective
  1. Of or pertaining to medicines; medical.
MEDIC noun
  1. Any of various European and North African herbs, of the genus Medicago, several of which are grown for fodder etc.

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